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PMID: 7576049 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Murine CD38: an immunoregulatory ectoenzyme.

Immunology today ·Vol. 16 ·No. 10 ·1995-10-00 ·Pages 469-73

Lund F, Solvason N, Grimaldi JC, Parkhouse RM, Howard M

Abstract

CD38 is an ectoenzyme that utilizes NAD+ and is expressed by many cells of hematopoietic origin. Antibodies to CD38 potentiate many biological activities on lymphocytes, including induction of murine B-cell proliferation. In this article, Frances Lund and colleagues summarize information concerning the expression, enzymatic activity and signal transduction pathway utilized by murine CD38.

MeSH Terms

ADP-ribosyl Cyclase ADP-ribosyl Cyclase 1 Animals Antigens, CD Antigens, Differentiation/immunology B-Lymphocytes/enzymology,immunology Lymphocyte Activation Membrane Glycoproteins Mice N-Glycosyl Hydrolases/immunology Signal Transduction

Chemicals

Antigens, CD Antigens, Differentiation Membrane Glycoproteins N-Glycosyl Hydrolases ADP-ribosyl Cyclase Cd38 protein, mouse ADP-ribosyl Cyclase 1

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Lund F

DNAX Research Institute, Palo Alto, CA 94304, USA.

Solvason N

Grimaldi J C

Parkhouse R M

Howard M

Article Info

Journal

Immunology today

Abbr.

Immunol Today

ISSN

0167-5699

DOI

10.1016/0167-5699(95)80029-8

Published

1995-10-00

Pages

469-73

Language

English

Region

England

NLM ID

8008346

Subset

External Links

PubMed source DOI: 10.1016/0167-5699(95)80029-8

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