New insights into V(D)J recombination and its role in the evolution of the immune system.

Animals Biological Evolution Cell Differentiation/genetics DNA Nucleotidyltransferases/physiology DNA Transposable Elements/genetics DNA-Binding Proteins Epitopes/genetics Gene Rearrangement, B-Lymphocyte/genetics,immunology Gene Rearrangement, T-Lymphocyte/genetics,immunology Genes, Immunoglobulin/genetics Homeodomain Proteins Humans Immune System/cytology,growth & development Nuclear Proteins Proteins/genetics Receptors, Antigen, B-Cell/genetics Receptors, Antigen, T-Cell, alpha-beta/genetics Receptors, Antigen, T-Cell, gamma-delta/genetics Recombination, Genetic/genetics Regulatory Sequences, Nucleic Acid/genetics VDJ Recombinases Vertebrates/genetics,immunology

DNA Transposable Elements DNA-Binding Proteins Epitopes Homeodomain Proteins Nuclear Proteins Proteins RAG2 protein, human Receptors, Antigen, B-Cell Receptors, Antigen, T-Cell, alpha-beta Receptors, Antigen, T-Cell, gamma-delta V(D)J recombination activating protein 2 RAG-1 protein DNA Nucleotidyltransferases VDJ Recombinases