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PMID: 7627458 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Review

Recognition and control of neisserial infection by antibody and complement.

Trends in microbiology ·Vol. 3 ·No. 5 ·1995-05-00 ·Pages 198-201

Jarvis GA

Abstract

Immunity to neisserial infection involves complex interactions between antibody, complement and bacterial cell-surface molecules. Neisseria species express polysaccharide and glycolipid membrane components, which downregulate complement activation. The pathogenic potential of Neisseria depends on evasion of the complement cascade.

MeSH Terms

Antibodies, Bacterial/immunology Antigens, Bacterial/immunology Carbohydrate Sequence Complement Activation/immunology Female Gonorrhea/immunology Humans Lipopolysaccharides/immunology Meningococcal Infections/immunology Molecular Sequence Data N-Acetylneuraminic Acid Sialic Acids/metabolism

Chemicals

Antibodies, Bacterial Antigens, Bacterial Lipopolysaccharides Sialic Acids lipid-linked oligosaccharides N-Acetylneuraminic Acid

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Jarvis G A

Dept of Laboratory Medicine, University of California, San Francisco 94121, USA.

Article Info

Journal

Trends in microbiology

Abbr.

Trends Microbiol

ISSN

0966-842X

DOI

10.1016/s0966-842x(00)88921-0

Published

1995-05-00

Pages

198-201

Language

English

Region

England

NLM ID

9310916

Subset

Grants

NIAID NIH HHS · AI21171 · United States

External Links

PubMed source DOI: 10.1016/s0966-842x(00)88921-0 View journal details

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Recognition and control of neisserial infection by antibody and complement.

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