Structure, properties, mechanisms, and assays of cysteine protease inhibitors: cystatins and E-64 derivatives.

Animals Cathepsins/isolation & purification,metabolism Chromatography, Affinity/methods Chromatography, DEAE-Cellulose/methods Chromatography, Gel/methods Cystatins/chemistry,isolation & purification,pharmacology Cysteine Endopeptidases/metabolism Cysteine Proteinase Inhibitors/chemistry,pharmacology Cytosol/enzymology Indicators and Reagents Kinetics Leucine/analogs & derivatives,chemistry,pharmacology Liver/metabolism Lysosomes/enzymology Papain/metabolism Rats Recombinant Proteins/isolation & purification,pharmacology Structure-Activity Relationship

Cystatins Cysteine Proteinase Inhibitors Indicators and Reagents Recombinant Proteins Cathepsins Cysteine Endopeptidases Papain Leucine E 64