Arf proteins: the membrane traffic police?

Trends in biochemical sciences ·Vol. 20 ·No. 4 ·1995-04-00 ·Pages 147-50

Boman AL, Kahn RA

Abstract

Cofactor for cholera toxin; activator of phospholipase D; regulator of coat-protein assembly; inhibitor of membrane traffic; ability to cause expansion of the endoplasmic reticulum and vesiculation of the Golgi; sensitivity to membrane phospholipids--each of these activities has been attributed to Arf proteins. Can a single molecular mechanism link them all?

MeSH Terms

ADP-Ribosylation Factors Animals GTP-Binding Proteins/chemistry,genetics,metabolism Humans Membrane Lipids/metabolism Models, Biological Models, Molecular Phospholipids/metabolism

Chemicals

Membrane Lipids Phospholipids GTP-Binding Proteins ADP-Ribosylation Factors

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Boman A L

Laboratory of Biological Chemistry, Developmental Therapeutics Program, DCT, NCI, Bethesda, MD 20892, USA.

Kahn R A

Article Info

Journal

Trends in biochemical sciences

Abbr.

Trends Biochem Sci

ISSN

0968-0004

DOI

10.1016/s0968-0004(00)88991-4

Published

1995-04-00

Pages

147-50

Language

English

Region

England

NLM ID

7610674

Subset

Corrections

CommentIn

PMID: 9581500

External Links

PubMed source DOI: 10.1016/s0968-0004(00)88991-4 View journal details

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Arf proteins: the membrane traffic police?

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