Telomere shortening in chronic liver diseases.

Biochemical and biophysical research communications ·Vol. 211 ·No. 1 ·1995-06-06 ·Pages 33-9

Kitada T, Seki S, Kawakita N, Kuroki T, Monna T

Abstract

We measured the telomere length in patients with chronic hepatitis or liver cirrhosis and found a significant telomere shortening in the liver with chronic liver disease compared to that in the normal liver. The telomere length tended to decrease with the progression of chronic liver disease.

MeSH Terms

Adult Aged Aging/physiology Base Sequence Blotting, Southern Female Hepatitis/genetics,pathology Humans Liver/cytology,metabolism,pathology Liver Cirrhosis/genetics,pathology Liver Neoplasms/genetics,pathology,secondary Male Middle Aged Molecular Sequence Data Oligonucleotide Probes Reference Values Telomere/pathology,ultrastructure

Chemicals

Oligonucleotide Probes

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Kitada T

Department of Public Health, Osaka City University Medical School, Japan.

Seki S

Kawakita N

Kuroki T

Monna T

Article Info

Journal

Biochemical and biophysical research communications

Abbr.

Biochem Biophys Res Commun

ISSN

0006-291X

DOI

10.1006/bbrc.1995.1774

Published

1995-06-06

Pages

33-9

Language

English

Region

United States

NLM ID

0372516

Subset

External Links

PubMed source DOI: 10.1006/bbrc.1995.1774 View journal details

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