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PMID: 7786501 Published · ppublish English Journal Article

Energy dispersive analysis of X-rays study of the distribution of chlorhexidine diacetate and cetylpyridinium chloride on the Pseudomonas aeruginosa bacteriophage F116.

Letters in applied microbiology ·Vol. 20 ·No. 6 ·1995-06-00 ·Pages 357-60

Maillard JY, Hann AC, Beggs TS, Day MJ, Hudson RA, Russell AD

Abstract

Using an energy dispersive analyser of X-rays fitted to a scanning electron microscope, chlorhexidine was shown not to bind onto F116 bacteriophage, unlike cetylpyridinium chloride, which possibly penetrated the phage. This could explain the difference in viricidal activity between the two compounds.

MeSH Terms
Bacteriophages/chemistry,drug effects Cetylpyridinium/analysis,pharmacology Chlorhexidine/analysis,pharmacology Electron Probe Microanalysis Pseudomonas aeruginosa/virology
Chemicals
Cetylpyridinium Chlorhexidine
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Maillard J Y
Welsh School of Pharmacy, Department of Applied Biology, University of Wales College of Cardiff, UK.
Hann A C
Beggs T S
Day M J
Hudson R A
Russell A D
Article Info
Journal
Letters in applied microbiology
Abbr.
Lett Appl Microbiol
ISSN
0266-8254
Published
1995-06-00
Pages
357-60
Language
English
Region
England
NLM ID
8510094
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