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PMID: 7868616 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Escherichia coli NusG protein stimulates transcription elongation rates in vivo and in vitro.

Journal of bacteriology ·Vol. 177 ·No. 5 ·1995-03-00 ·Pages 1388-92

Burova E, Hung SC, Sagitov V, Stitt BL, Gottesman ME

Abstract

The rate of transcription elongation in Escherichia coli was reduced when cells were depleted of NusG. In a purified in vitro system, NusG accelerated the transcription elongation rate. The stimulation of the rate of transcription elongation by NusG appears to result from the suppression of specific transcription pause sites.

Related Genes
nusG
MeSH Terms
Bacterial Proteins/genetics Base Sequence Calmodulin-Binding Proteins/genetics Drosophila Proteins Escherichia coli/genetics Escherichia coli Proteins Kinetics Membrane Proteins/genetics Molecular Sequence Data Peptide Elongation Factors/genetics RNA, Messenger/biosynthesis Suppression, Genetic Transcription Factors/genetics Transcription, Genetic Transient Receptor Potential Channels
Chemicals
Bacterial Proteins Calmodulin-Binding Proteins Drosophila Proteins Escherichia coli Proteins Membrane Proteins NusG protein, E coli Peptide Elongation Factors RNA, Messenger Transcription Factors Transient Receptor Potential Channels trpl protein, Drosophila
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Burova E
Institute of Cancer Research, College of Physicians and Surgeons of Columbia University, New York, New York 10032.
Hung S C
Sagitov V
Stitt B L
Gottesman M E
References (22)
22 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.177.5.1388-1392.1995
Published
1995-03-00
Pages
1388-92
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC176748
Subset
IM
Grants
NIGMS NIH HHS · GM37219 · United States
External Links
PubMed source DOI: 10.1128/jb.177.5.1388-1392.1995 PMC Full Text View journal details
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