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PMID: 7959058 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Histone-encoding genes from Pyrococcus: evidence for members of the HMf family of archaeal histones in a non-methanogenic Archaeon.

Gene ·Vol. 150 ·No. 1 ·1994-12-02 ·Pages 207-8

Sandman K, Perler FB, Reeve JN

Abstract

Two genes, designated hpyA1 and hpyA2, have been cloned and sequenced from Pyrococcus strain GB-3a. They are predicted to encode proteins (HPyA1 and HPyA2, respectively) that are approx. 60% identical to the histones HMf and HMt, characterized from methanogenic Archaea. These archaeal histones also contain the amino-acid sequences, conserved in eukaryotic H4 histones, that are thought to interact directly with DNA.

Related Genes

hmfA hmfB hpyA1 hpyA2

MeSH Terms

Amino Acid Sequence Archaea/genetics Archaeal Proteins Bacterial Proteins/genetics Base Sequence Cloning, Molecular DNA, Bacterial DNA-Binding Proteins/genetics Histones/genetics Molecular Sequence Data

Chemicals

Archaeal Proteins Bacterial Proteins DNA, Bacterial DNA-Binding Proteins HMf protein, Archaeal HPyA1 protein, Pyrococcus HPyA2 protein, Pyrococcus Histones

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Sandman K

Department of Microbiology, Ohio State University, Columbus 43210.

Perler F B

Reeve J N

Article Info

Journal

Gene

Abbr.

Gene

ISSN

0378-1119

DOI

10.1016/0378-1119(94)90890-7

Published

1994-12-02

Pages

207-8

Language

English

Region

Netherlands

NLM ID

7706761

Subset

Databases

GENBANK

U08837, U08838

External Links

PubMed source DOI: 10.1016/0378-1119(94)90890-7 View journal details

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Histone-encoding genes from Pyrococcus: evidence for members of the HMf family of archaeal histones in a non-methanogenic Archaeon.

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