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PMID: 796467 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Selective disadvantage of non-functional protein synthesis in Escherichia coli.

Journal of molecular evolution ·Vol. 8 ·No. 4 ·1976-12-30 ·Pages 317-28

Andrews KJ, Hegeman GD

Abstract

Comparison of growth rates of isogenic strains that synthesize varying levels of beta-galactosidase during continuous culture on non-inducing medium indicates that synthesis of low levels of non-functional protein has a small but possibly significant effect upon growth rate.

MeSH Terms
Bacterial Proteins/biosynthesis Biological Evolution Escherichia coli/enzymology,growth & development,metabolism Galactosidases/biosynthesis Lactose/biosynthesis Mutation Operon
Chemicals
Bacterial Proteins Galactosidases Lactose
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Andrews K J
Hegeman G D
References (22)
22 references, click to expand
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Article Info
Journal
Journal of molecular evolution
Abbr.
J Mol Evol
ISSN
0022-2844
DOI
10.1007/BF01739257
Published
1976-12-30
Pages
317-28
Language
English
Region
Germany
NLM ID
0360051
Subset
IM
External Links
PubMed source DOI: 10.1007/BF01739257 View journal details
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