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Eur J Immunol. 1992 Dec;22(12):3179-82
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Eur J Immunol. 1993 Sep;23(9):2136-43
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Effects of oral administration of type II collagen on rheumatoid arthritis.
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Oral tolerance in experimental autoimmune uveoretinitis. Distinct mechanisms of resistance are induced by low dose vs high dose feeding protocols.
J Immunol. 1993 Nov 15;151(10):5751-61
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Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes.
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Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.
Nature. 1993 Nov 4;366(6450):72-5
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Reactivity to myelin antigens in multiple sclerosis. Peripheral blood lymphocytes respond predominantly to myelin oligodendrocyte glycoprotein.
J Clin Invest. 1993 Dec;92(6):2602-8
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Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis.
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Oral tolerance in humans. T cell but not B cell tolerance after antigen feeding.
J Immunol. 1994 May 1;152(9):4663-70
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Development of reactivity to new myelin antigens during chronic relapsing autoimmune demyelination.
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Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens.
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Induction of anergy or active suppression following oral tolerance is determined by antigen dosage.
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Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis.
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Oral tolerance to myelin basic protein induces regulatory TGF-beta-secreting T cells in Peyer's patches of SJL mice.
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Antigen-driven tissue-specific suppression following oral tolerance: orally administered myelin basic protein suppresses proteolipid protein-induced experimental autoimmune encephalomyelitis in the SJL mouse.
Eur J Immunol. 1994 Sep;24(9):2104-9
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Cholera toxin B subunit: an efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance.
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The in vitro production of cytokines by mucosal lymphocytes immunized by oral administration of keyhole limpet hemocyanin using cholera toxin as an adjuvant.
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Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy.
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Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen.
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Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, and prostaglandin E expression in the brain.
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Double-blind pilot trial of oral tolerization with myelin antigens in multiple sclerosis.
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