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PMID: 7987013 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Nucleotide sequence of the 85B-protein gene of Mycobacterium bovis BCG and Mycobacterium tuberculosis.

DNA sequence : the journal of DNA sequencing and mapping ·Vol. 4 ·No. 4 ·1994-00-00 ·Pages 267-70

De Wit L, Palou M, Content J

Abstract

We have cloned and sequenced the genes coding for the 85B antigen from M. bovis BCG and M. tuberculosis. Within this gene, the only difference in sequence between M. bovis BCG and M. tuberculosis corresponds, respectively, to a C-->T yielding a Leu-->Phe replacement at position 100 of the mature 85B protein. Therefore as we described previously for the 85A gene, there is also very little variation between these two species within the 85B gene.

MeSH Terms

Acyltransferases Amino Acid Sequence Antigens, Bacterial/genetics Bacterial Proteins/genetics Base Sequence DNA, Bacterial/genetics Genes, Bacterial Molecular Sequence Data Mycobacterium avium/genetics Mycobacterium bovis/genetics Mycobacterium leprae/genetics Mycobacterium tuberculosis/genetics Nontuberculous Mycobacteria/genetics Sequence Alignment Sequence Homology, Amino Acid Species Specificity

Chemicals

Antigens, Bacterial Bacterial Proteins DNA, Bacterial antigen 85, Mycobacterium bovis Acyltransferases antigen 85B, Mycobacterium tuberculosis

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

De Wit L

Institut Pasteur du Brabant, Department of Virology, Bruxelles, Belgium.

Palou M

Content J

Article Info

Journal

DNA sequence : the journal of DNA sequencing and mapping

Abbr.

DNA Seq

ISSN

1042-5179

Published

1994-00-00

Pages

267-70

Language

English

Region

England

NLM ID

9107800

Subset

Databases

GENBANK

X62397, X62398

External Links

PubMed source

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Nucleotide sequence of the 85B-protein gene of Mycobacterium bovis BCG and Mycobacterium tuberculosis.

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