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PMID: 8019422 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Enlarged representative set of protein structures.

Protein science : a publication of the Protein Society ·Vol. 3 ·No. 3 ·1994-03-00 ·Pages 522-4

Hobohm U, Sander C

Abstract

To reduce redundancy in the Protein Data Bank of 3D protein structures, which is caused by many homologous proteins in the data bank, we have selected a representative set of structures. The selection algorithm was designed to (1) select as many nonhomologous structures as possible, and (2) to select structures of good quality. The representative set may reduce time and effort in statistical analyses.

MeSH Terms
Amino Acid Sequence Crystallography, X-Ray Databases, Factual/standards Models, Chemical Molecular Structure Proteins/chemistry,genetics Quality Control Sequence Homology, Amino Acid
Chemicals
Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Hobohm U
European Molecular Biology Laboratory, Heidelberg, Germany.
Sander C
References (5)
5 references, click to expand
  1. The Protein Data Bank: a computer-based archival file for macromolecular structures.
    J Mol Biol. 1977 May 25;112(3):535-42 PMID: 875032
  2. Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features.
    Biopolymers. 1983 Dec;22(12):2577-637 PMID: 6667333
  3. Prediction of protein secondary structure at better than 70% accuracy.
    J Mol Biol. 1993 Jul 20;232(2):584-99 PMID: 8345525
  4. A database of protein structure families with common folding motifs.
    Protein Sci. 1992 Dec;1(12):1691-8 PMID: 1304898
  5. Selection of representative protein data sets.
    Protein Sci. 1992 Mar;1(3):409-17 PMID: 1304348
Article Info
Journal
Protein science : a publication of the Protein Society
Abbr.
Protein Sci
ISSN
0961-8368
Published
1994-03-00
Pages
522-4
Language
English
Region
United States
NLM ID
9211750
PMCID
PMC2142698
Subset
IM
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