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PMID: 804990 Published · ppublish English Journal Article

A new, mouse-myeloma immunoglobulin A having specificity for beta-D-(1 yields 6)-linked D-galactopyranosyl residues.

Carbohydrate research ·Vol. 40 ·No. 1 ·1975-03-00 ·Pages 137-42

Manjula BN, Glaudemans CP, Mushinski E, Potter M

Abstract

The discovery of T601, a new mouse-myeloma immunoglobulin A having specificity for beta-D-(1 yields 6)-linked D-galactopyranosyl residues, brings the total number of known antigalactan immunoglobulins to seven. The interaction of T601 with a number of ligands has been investigated. For those ligands showing interaction with the immunoglobulin, the affinity constants have been quantitatively measured by tryptophanyl fluorescence. The values show that protein T601 behaves very similarly to protein X24.

MeSH Terms
Animals Binding Sites Galactose Glycosides Immunodiffusion Immunoglobulin A Isoelectric Focusing Kinetics Mice/immunology Myeloma Proteins Protein Binding Rabbits/immunology Spectrometry, Fluorescence Structure-Activity Relationship
Chemicals
Glycosides Immunoglobulin A Myeloma Proteins Galactose
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Manjula B N
Glaudemans C P
Mushinski E
Potter M
Article Info
Journal
Carbohydrate research
Abbr.
Carbohydr Res
ISSN
0008-6215
Published
1975-03-00
Pages
137-42
Language
English
Region
Netherlands
NLM ID
0043535
Subset
IM
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