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PMID: 809840 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Vasopressin: induced structural change in toad bladder luminal membrane.

Science (New York, N.Y.) ·Vol. 190 ·No. 4209 ·1975-10-03 ·Pages 67-9

Kachadorian WA, Wade JB, DiScala VA

Abstract

Freeze-fracture electron microscopy demonstrates that vasopressin stimulation of isolated toad bladder alters the structure of the luminal membrane of granular cells. This alteration consists of an ordered aggression of intramembranous particles, and appears to be of functional significance, since the frequency of aggregation sites per area of membrane is closely correlated with vasopressin-induced osmotic water flow.

MeSH Terms
Animals Bufo marinus Cell Membrane/drug effects,ultrastructure Dose-Response Relationship, Drug Female In Vitro Techniques Permeability Urinary Bladder/cytology,drug effects,ultrastructure Vasopressins/pharmacology Water/metabolism
Chemicals
Water Vasopressins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Kachadorian W A
Wade J B
DiScala V A
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1975-10-03
Pages
67-9
Language
English
Region
United States
NLM ID
0404511
Subset
IM
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