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PMID: 8110957 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Tuberculous meningitis: a 30-year review.

Kent SJ, Crowe SM, Yung A, Lucas CR, Mijch AM

Abstract

Tuberculous meningitis remains an important illness that can be difficult to diagnose in a timely fashion and carries significant morbidity. We present a retrospective review of the cases of tuberculous meningitis diagnosed and treated at a single institution. Fifty-eight cases were identified and stratified according to stage of disease at presentation. Four patients (7%) died; three (5%) developed severe neurological sequelae. Poor outcomes were largely confined to cases presenting in an advanced stage and at the extremes of age. Corticosteroids were administered to 56 patients and may have contributed to the comparatively good outcome in these cases.

MeSH Terms
Adrenal Cortex Hormones/therapeutic use Antitubercular Agents/therapeutic use Australia Cerebrospinal Fluid/chemistry,cytology,microbiology Humans Mycobacterium tuberculosis/isolation & purification Time Factors Tuberculosis, Meningeal/cerebrospinal fluid,diagnosis,drug therapy
Chemicals
Adrenal Cortex Hormones Antitubercular Agents
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Kent S J
Fairfield Infectious Diseases Hospital, Victoria, Australia.
Crowe S M
Yung A
Lucas C R
Mijch A M
Article Info
Journal
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Abbr.
Clin Infect Dis
ISSN
1058-4838
Published
1993-12-00
Pages
987-94
Language
English
Region
United States
NLM ID
9203213
Subset
IM
Corrections
CommentIn
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