To examine if increased egg consumption raises serum high-density-lipoprotein (HDL) cholesterol in healthy individuals. A cross-over study. A private clinic for preventive health examinations in Copenhagen. Twenty-four healthy adults, 12 men and 12 women, aged 23-52 (median 40) years. After a 1-week control period each person added two boiled eggs to the usual daily diet for 6 weeks. All persons were instructed not to change the lifestyle in other ways during the whole study period. Serum HDL cholesterol, total cholesterol and triglycerides were measured before, during and after 6 weeks of extra egg consumption. The corresponding serum low-density-lipoprotein (LDL) cholesterol was calculated from the Friedewald formula. After 6 weeks of extra egg consumption serum HDL cholesterol increased by 10% (P < 0.05) and total cholesterol increased 4% (P < 0.05), whereas the ratio total cholesterol/HDL cholesterol did not change significantly. Serum triglycerides and LDL cholesterol were also unchanged. A moderate egg intake should not be rigorously restricted in healthy individuals.
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