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PMID: 8129947 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

The regulation of export of mRNA from nucleus to cytoplasm.

Current opinion in cell biology ·Vol. 5 ·No. 6 ·1993-12-00 ·Pages 944-9

Krug RM

Abstract

The past year has been marked by the discovery that the influenza virus NS1 protein belongs to the group of viral proteins that regulate the nuclear export of mRNA. This protein, like other viral proteins in this group, such as the Rev protein of human immunodeficiency virus 1 (HIV-1) and the complex of two adenovirus early proteins, has the potential to provide insights into the poorly understood process of the nuclear export of mRNA.

MeSH Terms

Adenoviridae/genetics,metabolism Animals Biological Transport Cell Nucleus/metabolism Cytoplasm/metabolism Gene Products, rev/physiology HIV-1/genetics,metabolism Nuclear Envelope/metabolism Orthomyxoviridae/genetics,metabolism RNA Precursors/metabolism RNA Processing, Post-Transcriptional RNA, Messenger/metabolism RNA, Viral/metabolism Viral Nonstructural Proteins/physiology Viral Proteins/metabolism rev Gene Products, Human Immunodeficiency Virus

Chemicals

Gene Products, rev INS1 protein, influenza virus RNA Precursors RNA, Messenger RNA, Viral Viral Nonstructural Proteins Viral Proteins rev Gene Products, Human Immunodeficiency Virus

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Krug R M

Rutgers University, Piscataway.

Article Info

Journal

Current opinion in cell biology

Abbr.

Curr Opin Cell Biol

ISSN

0955-0674

DOI

10.1016/0955-0674(93)90074-z

Published

1993-12-00

Pages

944-9

Language

English

Region

England

NLM ID

8913428

Subset

Grants

NIAID NIH HHS · AI 11772 · United States

External Links

PubMed source DOI: 10.1016/0955-0674(93)90074-z View journal details

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The regulation of export of mRNA from nucleus to cytoplasm.

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