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PMID: 8144489 Published · ppublish English Journal Article Review

Mechanisms of TonB-catalyzed iron transport through the enteric bacterial cell envelope.

Journal of bioenergetics and biomembranes ·Vol. 25 ·No. 6 ·1993-12-00 ·Pages 603-11

Klebba PE, Rutz JM, Liu J, Murphy CK

Abstract

The recent solution of enteric bacterial porin structure, and new insights into the mechanism by which outer membrane receptor proteins recognize and internalize specific ligands, advocates the re-evaluation of TonB-dependent transport physiology. In this minireview we discuss the potential structural features of siderophore receptors and TonB, and use this analysis to evaluate both existing and new models of energy and signal transduction from the inner membrane to the outer membrane of gram-negative bacteria.

MeSH Terms
Amino Acid Sequence Bacterial Proteins/chemistry,metabolism Biological Transport Cell Membrane/metabolism Enterobacteriaceae/metabolism Escherichia coli/metabolism Escherichia coli Proteins Iron/metabolism Membrane Proteins/chemistry,metabolism Models, Molecular Models, Structural Molecular Sequence Data Protein Conformation Protein Structure, Secondary
Chemicals
Bacterial Proteins Escherichia coli Proteins Membrane Proteins tonB protein, Bacteria tonB protein, E coli Iron
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Klebba P E
Department of Microbiology, Medical College of Wisconsin, Milwaukee 53226.
Rutz J M
Liu J
Murphy C K
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Article Info
Journal
Journal of bioenergetics and biomembranes
Abbr.
J Bioenerg Biomembr
ISSN
0145-479X
DOI
10.1007/BF00770247
Published
1993-12-00
Pages
603-11
Language
English
Region
United States
NLM ID
7701859
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00770247 View journal details
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