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PMID: 8146911 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Review

The 530 loop of 16S rRNA: a signal to EF-Tu?

Trends in genetics : TIG ·Vol. 10 ·No. 1 ·1994-01-00 ·Pages 27-31

Powers T, Noller HF

Abstract

The molecular mechanism of tRNA selection has remained elusive. Recent evidence, both biochemical and genetic, suggests the involvement of 'smart' ribosomes, that can signal the elongation factor Tu by way of conformational changes in ribosomal RNA.

MeSH Terms
Models, Biological Nucleic Acid Conformation Peptide Chain Elongation, Translational Peptide Elongation Factor Tu/chemistry,metabolism Protein Conformation RNA, Ribosomal, 16S/chemistry,metabolism RNA, Transfer/metabolism Ribosomal Proteins/genetics
Chemicals
RNA, Ribosomal, 16S Ribosomal Proteins ribosomal protein S12 RNA, Transfer Peptide Elongation Factor Tu
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Powers T
Sinsheimer Laboratories, University of California, Santa Cruz 95064.
Noller H F
Article Info
Journal
Trends in genetics : TIG
Abbr.
Trends Genet
ISSN
0168-9525
DOI
10.1016/0168-9525(94)90016-7
Published
1994-01-00
Pages
27-31
Language
English
Region
England
NLM ID
8507085
Subset
IM
Grants
NIGMS NIH HHS · GM17129 · United States
External Links
PubMed source DOI: 10.1016/0168-9525(94)90016-7 View journal details
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