Home LiteratureArticle Details
PMID: 815243 Published · ppublish English Journal Article

Translocation in Bacillus subtilis: irreversible inactivation of elongation factor G and viability of a temperature- sensitive mutant.

Journal of bacteriology ·Vol. 125 ·No. 3 ·1976-03-00 ·Pages 1229-31

Aharonowitz Y, Ron EZ

Abstract

A temperature-sensitive mutant of Bacillus subtilis 168 lost its viability irreversibly when grown at temperatures higher than 50 C. It is suggested that this loss of viability is due to irreversible alteration of elongation factor G activity, which was shown in vitro by two different assay methods.

MeSH Terms
Bacillus subtilis/enzymology,growth & development,metabolism Cell-Free System Chloramphenicol/pharmacology Chromosome Aberrations GTP Phosphohydrolase-Linked Elongation Factors/metabolism Mutation Peptide Biosynthesis Peptide Elongation Factors Puromycin Temperature Translocation, Genetic
Chemicals
Peptide Elongation Factors Puromycin Chloramphenicol GTP Phosphohydrolase-Linked Elongation Factors
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Aharonowitz Y
Ron E Z
References (5)
5 references, click to expand
  1. TRANSFORMATION OF BIOCHEMICALLY DEFICIENT STRAINS OF BACILLUS SUBTILIS BY DEOXYRIBONUCLEATE.
    Proc Natl Acad Sci U S A. 1958 Oct 15;44(10):1072-8 PMID: 16590310
  2. Comparison of guanosine triphosphate split and polypeptide synthesis with a purified E. coli system.
    Proc Natl Acad Sci U S A. 1966 Jan;55(1):212-9 PMID: 4287350
  3. Control of stable RNA synthesis in a temperature-sensitive mutant of elongation factor G of Bacillus subtilis.
    Mol Gen Genet. 1974 May 31;130(3):203-14 PMID: 4210680
  4. A temperature sensitive mutant in Bacillus subtilis with an altered elongation factor G.
    Mol Gen Genet. 1972;119(2):131-8 PMID: 4629789
  5. Translocation in Bacillus subtilis: characterization of elongation factor G by peptidyl-[3H]puromycin synthesis.
    J Bacteriol. 1976 Mar;125(3):1074-9 PMID: 815236
Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.125.3.1229-1231.1976
Published
1976-03-00
Pages
1229-31
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC236208
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.125.3.1229-1231.1976 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2