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PMID: 8178363 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Mechanisms for selecting 5' splice sites in mammalian pre-mRNA splicing.

Trends in genetics : TIG ·Vol. 10 ·No. 3 ·1994-03-00 ·Pages 100-6

Horowitz DS, Krainer AR

Abstract

Identification of 5' splice sites requires that limited and dispersed sequence information be interpreted precisely. Both snRNAs and proteins are required for this process. The selection of 5' splice sites in alternative splicing is closely related to that in constitutive splicing, and uses the same components in somewhat different ways.

MeSH Terms
Animals Base Sequence Consensus Sequence Humans Models, Genetic Molecular Sequence Data RNA Precursors/genetics RNA Splicing/physiology Ribonucleoprotein, U1 Small Nuclear/physiology Ribonucleoproteins/physiology
Chemicals
RNA Precursors Ribonucleoprotein, U1 Small Nuclear Ribonucleoproteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Horowitz D S
Cold Spring Harbor Laboratory, NY 11724.
Krainer A R
Article Info
Journal
Trends in genetics : TIG
Abbr.
Trends Genet
ISSN
0168-9525
DOI
10.1016/0168-9525(94)90233-x
Published
1994-03-00
Pages
100-6
Language
English
Region
England
NLM ID
8507085
Subset
IM
Grants
NCI NIH HHS · CA13106 · United States
NIGMS NIH HHS · GM42699 · United States
External Links
PubMed source DOI: 10.1016/0168-9525(94)90233-x View journal details
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