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PMID: 822278 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Conditional mutations in the translational apparatus of Bacillus subtils.

Molecular & general genetics : MGG ·Vol. 147 ·No. 1 ·1976-08-10 ·Pages 1-12

Dubnau E, Pifko S, Sloma A, Cabane K, Smith I

Abstract

Four temperature sensitive mutants of B. subtilis were isolated by localized mutagenesis in the major ribosomal gene cluster, and charcterized genetically and biochemically. Three are mutations which cause temperature sensitivity in the elongation factor Ef-G, and one which has a similar effect on the elongation factor Ef-Tu. They map in a cluster near strA, with the temperature sensitive mutations in Ef-G mapping between the strA gene and the temperature sensitive mutation in Ef-TU.

MeSH Terms
Bacillus subtilis Chromosome Mapping Chromosomes, Bacterial Genes Mutation Phenotype Protein Biosynthesis RNA, Bacterial/biosynthesis RNA, Ribosomal/biosynthesis Recombination, Genetic Ribosomes/metabolism Temperature
Chemicals
RNA, Bacterial RNA, Ribosomal
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Dubnau E
Pifko S
Sloma A
Cabane K
Smith I
References (36)
36 references, click to expand
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00337929
Published
1976-08-10
Pages
1-12
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00337929
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