Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20.

Fgf3 Hox Krox20

Amino Acid Sequence Animals Animals, Newborn Base Sequence Blastocyst/physiology Blotting, Southern DNA/analysis DNA Primers DNA-Binding Proteins/genetics Early Growth Response Protein 2 Embryo, Mammalian Female Gene Deletion Genes, Lethal Genomic Library Genotype Glossopharyngeal Nerve/abnormalities Homozygote Male Mice Molecular Sequence Data Phenotype Polymerase Chain Reaction Restriction Mapping Rhombencephalon/abnormalities,embryology Transcription Factors/genetics Trigeminal Ganglion/abnormalities Vagus Nerve/abnormalities Zinc Fingers/genetics

DNA Primers DNA-Binding Proteins Early Growth Response Protein 2 Egr2 protein, mouse Transcription Factors DNA