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PMID: 8233634 Published · ppublish fre Journal Article

[Evaluation of a micromethod for the bactericidal activity of five disinfectants on 108 hospital strains].

Evaluation par une microméthode de l'activité bactéricide de cinq désinfectants sur 108 souches hospitalières.

Pathologie-biologie ·Vol. 41 ·No. 4 ·1993-04-00 ·Pages 349-57

Dusseau JY, Chapalain JC, Rouby Y, Reverdy ME, Bartoli M

Abstract

The authors studied 5 disinfectants containing aldehyde and quaternary ammonium against 108 hospital strains. The minimal bactericidal activities (MBC) were determined with a microdilution method and the dilution-neutralization method (AFNOR T 72-150). The microdilution method results were validated using the MBCs of four reference strains tested with the dilution-neutralization method (AFNOR T 72-150). 3 disinfectants proved to be valuable. 1 disinfectant was valuable but with a MBC toward all bacteria only a dilution away from the dilution of use. 1 disinfectant was determined as unsatisfactory as 9.5 p. cent of all strains proved resistant toward it. All disinfectants matched AFNOR standards; but those specifications did not match toward hospital strains. Such an evaluation using a simple and reliable method should be of use.

MeSH Terms
Acinetobacter/drug effects Disinfectants/pharmacology Dose-Response Relationship, Drug Enterococcus faecalis/drug effects Escherichia coli/drug effects Humans In Vitro Techniques Klebsiella/drug effects Proteus/drug effects Pseudomonas aeruginosa/drug effects Staphylococcus aureus/drug effects Staphylococcus epidermidis/drug effects
Chemicals
Disinfectants
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Dusseau J Y
Laboratoire de Biologie Médicale, Hôpital d'Instruction des Armées Desgenettes, Lyon, France.
Chapalain J C
Rouby Y
Reverdy M E
Bartoli M
Article Info
Journal
Pathologie-biologie
Abbr.
Pathol Biol (Paris)
ISSN
0369-8114
Published
1993-04-00
Pages
349-57
Language
fre
Region
France
NLM ID
0265365
Subset
IM
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