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PMID: 8240820 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

The structure and regulation of tight junctions.

Current opinion in cell biology ·Vol. 5 ·No. 5 ·1993-10-00 ·Pages 772-8

Anderson JM, Balda MS, Fanning AS

Abstract

Tight junctions create a paracellular barrier between both epithelial and endothelial cells. Recent advances have helped define their molecular composition and regulation. Studies in cultured cell lines provide new insights into how assembly and barrier properties may be controlled by signal transduction cascades.

MeSH Terms

Animals Cell Communication/physiology Intercellular Junctions/physiology,ultrastructure Membrane Proteins/biosynthesis,physiology Models, Biological Phosphoproteins/biosynthesis,physiology Signal Transduction Zonula Occludens-1 Protein

Chemicals

Membrane Proteins Phosphoproteins Zonula Occludens-1 Protein

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Anderson J M

Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut 06510.

Balda M S

Fanning A S

Article Info

Journal

Current opinion in cell biology

Abbr.

Curr Opin Cell Biol

ISSN

0955-0674

DOI

10.1016/0955-0674(93)90024-k

Published

1993-10-00

Pages

772-8

Language

English

Region

England

NLM ID

8913428

Subset

Grants

NIDDK NIH HHS · DK 34989 · United States

NIDDK NIH HHS · DK 45134 · United States

NIDDK NIH HHS · T32 DK 07356 · United States

External Links

PubMed source DOI: 10.1016/0955-0674(93)90024-k View journal details

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The structure and regulation of tight junctions.

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