Release of vasoactive intestinal polypeptide (VIP) by electric stimulation of the vagal nerves.

Gastroenterology ·Vol. 72 ·No. 2 ·1977-02-00 ·Pages 373-5

Schaffalitzky de Muckadell OB, Fahrenkrug J, Holst JJ

Abstract

The concentration of immunoreactive VIP was measured in portal venous and peripheral arterial plasma in anesthetized pigs. Following electric stimulation of the vagal nerves the median concentration of VIP in portal plasma rose from 21 to 58 pmol l-1 and a simultaneous increase was found in arterial plasma. Atropine did not abolish this effect of vagal stimulation. The response is interpreted as increased release of VIP.

MeSH Terms

Animals Electric Stimulation Female Gastrointestinal Hormones/metabolism Swine Vagus Nerve/physiology Vasoactive Intestinal Peptide/immunology,metabolism

Chemicals

Gastrointestinal Hormones Vasoactive Intestinal Peptide

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Schaffalitzky de Muckadell O B

Fahrenkrug J

Holst J J

Article Info

Journal

Gastroenterology

Abbr.

Gastroenterology

ISSN

0016-5085

Published

1977-02-00

Pages

373-5

Language

English

Region

United States

NLM ID

0374630

Subset

External Links

PubMed source View journal details

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Release of vasoactive intestinal polypeptide (VIP) by electric stimulation of the vagal nerves.

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