Home LiteratureArticle Details
PMID: 8307452 Published · ppublish English Journal Article

Coeliac disease in the elderly.

Gut ·Vol. 35 ·No. 1 ·1994-01-00 ·Pages 65-7

Hankey GL, Holmes GK

Abstract

Of 228 patients with adult coeliac disease, 42 (19%) were diagnosed aged 60 years or over. In this series, of 35 patients who did not have dermatitis herpetiformis, 15 had attended family doctors and hospital outpatient departments for an average of 28 years with unexplained symptoms or abnormalities in blood tests but the diagnosis of coeliac disease had been missed. This is unsatisfactory because these patients can both manage and respond to a gluten free diet. Thirty eight patients complied strictly with the diet with resolution of symptoms. Significant improvement in weight, haemoglobin, albumin, calcium, and alkaline phosphatase values after a year on the diet also occurred. Clinicians should be alert to the possibility of coeliac disease in the elderly particularly in patients with non-specific complaints in the presence of unexplained anaemia.

MeSH Terms
Adolescent Adult Age Factors Aged Aged, 80 and over Anemia/etiology Celiac Disease/complications,diagnosis,diet therapy Dermatitis Herpetiformis/etiology Diagnostic Errors Female Glutens/administration & dosage Humans Male Middle Aged Patient Compliance Sex Factors Time Factors
Chemicals
Glutens
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Hankey G L
Department of Gastroenterology, Derbyshire Royal Infirmary, Derby.
Holmes G K
References (10)
10 references, click to expand
  1. Lymphoma risk in coeliac disease of later life.
    Digestion. 1982;23(2):89-92 PMID: 7095316
  2. Adult celiac sprue: changes in the pattern of clinical recognition.
    J Clin Gastroenterol. 1988 Aug;10(4):395-400 PMID: 3418086
  3. Is jejunal biopsy valuable in the elderly?
    Age Ageing. 1978 Nov;7(4):244-5 PMID: 727074
  4. Clinical presentation of coeliac disease in adult gastroenterological practice.
    Ulster Med J. 1985 Oct;54(2):140-7 PMID: 4095802
  5. Perforation from endoscopic small bowel biopsy.
    Gut. 1993 Jan;34(1):134-5 PMID: 8432444
  6. Malignancy in coeliac disease--effect of a gluten free diet.
    Gut. 1989 Mar;30(3):333-8 PMID: 2707633
  7. The clinical behavior of sprue in the United States.
    Gastroenterology. 1960 Mar;38:399-418 PMID: 13851526
  8. Upper gastrointestinal endoscopy in high risk patients under conscious sedation: is intensive monitoring necessary?
    Am J Gastroenterol. 1992 Apr;87(4):542 PMID: 1553948
  9. IgA anti-gliadin antibodies in adult celiac disease.
    Clin Chem. 1991 May;37(5):647-50 PMID: 2032317
  10. Is coeliac disease underdiagnosed?
    Br Med J. 1980 Nov 8;281(6250):1258-60 PMID: 7427659
Article Info
Journal
Gut
Abbr.
Gut
ISSN
0017-5749
Published
1994-01-00
Pages
65-7
Language
English
Region
England
NLM ID
2985108R
PMCID
PMC1374634
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]