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PMID: 8314593 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Exon structure of the human dystrophin gene.

Genomics ·Vol. 16 ·No. 2 ·1993-05-00 ·Pages 536-8

Roberts RG, Coffey AJ, Bobrow M, Bentley DR

Abstract

Application of a novel vectorette PCR approach to defining intron-exon boundaries has permitted completion of analysis of the exon structure of the largest and most complex known human gene. We present here a summary of the exon structure of the entire human dystrophin gene, together with the sizes of genomic HindIII fragments recognized by each exon, and (where available) GenBank accession numbers for adjacent intron sequences.

MeSH Terms
Chromosomes, Fungal Dystrophin/genetics Exons Gene Library Genes Genetic Vectors Genome, Human Humans Molecular Sequence Data Polymerase Chain Reaction/methods
Chemicals
Dystrophin
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Roberts R G
Paediatric Research Unit, Division of Medical & Molecular Genetics, London, United Kingdom.
Coffey A J
Bobrow M
Bentley D R
Article Info
Journal
Genomics
Abbr.
Genomics
ISSN
0888-7543
Published
1993-05-00
Pages
536-8
Language
English
Region
United States
NLM ID
8800135
Subset
IM
Databases
GENBANK
L05636, L05637, L05638, L05639, L05640, L05641, L05642, L05643, L05644, L05645, L05646, L05650, M55699, M59228, M81257, X06293, X13045, X13046, X13048, X15495, X54820, X65341, X65342, X65343, X65347, X65348, X65349, X65350, X65351, X65352
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