Intragenic suppression at the b2 locus in Ascobolus immersus. I. Identification of three distinct groups of suppression.

Genetics ·Vol. 90 ·No. 3 ·1978-11-00 ·Pages 475-88

Leblon G, Paquette N

Abstract

A reversion study of EMS- or ICR170-induced ascospore color mutants in Ascobolus immersus is reported. Twenty-three new intragenic suppressors were isolated within the b2 locus. These are localized within three distinct groups on a genetic fine-structure map containing 21 identifiable sites. The pattern of reversion is discussed according to the known specificity of EMS and ICR170 in Ascobolus immersus.

MeSH Terms

Ascomycota/genetics Ethyl Methanesulfonate/pharmacology Genetic Linkage Nitrogen Mustard Compounds/pharmacology Pigmentation Suppression, Genetic/drug effects

Chemicals

Nitrogen Mustard Compounds Ethyl Methanesulfonate

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Leblon G

Paquette N

References (9)

9 references, click to expand

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A genetic and biochemical analysis of second site reversion.
J Biol Chem. 1963 Mar;238:1043-8 PMID: 13953567
Amino acid replacements and the genetic code.
Cold Spring Harb Symp Quant Biol. 1966;31:151-62 PMID: 4866372
Altered amino acid sequences produced by reversion of frameshift mutants of tryptophan synthetase A gene of E. coli.
Proc Natl Acad Sci U S A. 1967 Oct;58(4):1499-506 PMID: 4867662
Frameshifts and frameshift suppressors in Saccharomyces cerevisiae.
Genetics. 1977 Aug;86(4):745-64 PMID: 72702
Nonsense codons.
Cold Spring Harb Symp Quant Biol. 1966;31:173-9 PMID: 5237189
Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday.
Cold Spring Harb Symp Quant Biol. 1966;31:77-84 PMID: 5237214
Base composition of nonsense codons in E. coli. Evidence from amino-acid substitutions at a tryptophan site in alkaline phosphatase.
Nature. 1965 Jun 5;206(988):992-4 PMID: 5320271
External suppression of a frameshift mutant in salmonella.
J Mol Biol. 1968 Jun 28;34(3):541-57 PMID: 4938557

Article Info

Journal

Genetics

Abbr.

Genetics

ISSN

0016-6731

DOI

10.1093/genetics/90.3.475

Published

1978-11-00

Pages

475-88

Language

English

Region

United States

NLM ID

0374636

PMCID

PMC1213901

Subset

External Links

PubMed source DOI: 10.1093/genetics/90.3.475 PMC Full Text View journal details

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Intragenic suppression at the b2 locus in Ascobolus immersus. I. Identification of three distinct groups of suppression.

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