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PMID: 8332534 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The translational termination signal database.

Nucleic acids research ·Vol. 21 ·No. 13 ·1993-07-01 ·Pages 3119-23

Brown CM, Dalphin ME, Stockwell PA, Tate WP

Abstract

The Translational Termination Database (TransTerm) consists of the immediate context sequences around the natural termination codons from 45 organisms, and summary tables. The influence of termination codon context on their effectivness as stop signals has been widely documented. The SPECIES--TRI.DAT table shows trinucleotide stop codon usage in each organism and for comparison the occurrence of these sequences in the noncoding region. The SPECIES--TETRA.DAT table contains is a similar table of tetranucleotide stop signal usage. The database is available from EMBL.

MeSH Terms
Animals Base Sequence Codon Databases, Factual Humans Molecular Sequence Data Peptide Chain Termination, Translational/genetics Species Specificity
Chemicals
Codon
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Brown C M
Department of Biochemistry, University of Otago, Dunedin, New Zealand.
Dalphin M E
Stockwell P A
Tate W P
References (15)
15 references, click to expand
  1. Eukaryotic start and stop translation sites.
    Nucleic Acids Res. 1991 Jun 25;19(12):3185-92 PMID: 1905801
  2. Recoding: reprogrammed genetic decoding.
    Science. 1992 Sep 18;257(5077):1640-1 PMID: 1529352
  3. Transfer ribonucleic acid-mediated suppression of termination codons in Escherichia coli.
    Microbiol Rev. 1988 Sep;52(3):354-74 PMID: 3054467
  4. Nonrandom utilization of codon pairs in Escherichia coli.
    Proc Natl Acad Sci U S A. 1989 May;86(10):3699-703 PMID: 2657727
  5. The signal for the termination of protein synthesis in procaryotes.
    Nucleic Acids Res. 1990 Apr 25;18(8):2079-86 PMID: 2186375
  6. The where, what and how of ribosomal frameshifting in retroviral protein synthesis.
    Trends Biochem Sci. 1990 May;15(5):186-90 PMID: 2193436
  7. Analysis of the stop codon context in plant nuclear genes.
    FEBS Lett. 1990 Oct 1;271(1-2):144-6 PMID: 2226798
  8. Sequence analysis suggests that tetra-nucleotides signal the termination of protein synthesis in eukaryotes.
    Nucleic Acids Res. 1990 Nov 11;18(21):6339-45 PMID: 2123028
  9. UGA can be decoded as tryptophan at low efficiency in Bacillus subtilis.
    J Bacteriol. 1991 Mar;173(5):1810-2 PMID: 1900283
  10. Effects of the nucleotide 3' to an amber codon on ribosomal selection rates of suppressor tRNA and release factor-1.
    J Mol Biol. 1991 May 20;219(2):231-41 PMID: 2038055
  11. Selenocysteine: the 21st amino acid.
    Mol Microbiol. 1991 Mar;5(3):515-20 PMID: 1828528
  12. Translational termination: "stop" for protein synthesis or "pause" for regulation of gene expression.
    Biochemistry. 1992 Mar 10;31(9):2443-50 PMID: 1547227
  13. GenBank.
    Nucleic Acids Res. 1992 May 11;20 Suppl:2065-9 PMID: 1598235
  14. The EMBL Data Library.
    Nucleic Acids Res. 1992 May 11;20 Suppl:2071-4 PMID: 1598236
  15. Selective differences among translation termination codons.
    Gene. 1988;63(1):141-5 PMID: 3133285
Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/21.13.3119
Published
1993-07-01
Pages
3119-23
Language
English
Region
England
NLM ID
0411011
PMCID
PMC309741
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/21.13.3119 PMC Full Text View journal details
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