Cyclic AMP synthesis in Xenopus laevis oocytes: inhibition by progesterone.

Biochimica et biophysica acta ·Vol. 582 ·No. 1 ·1979-01-04 ·Pages 179-84

Mulner O, Huchon D, Thibier C, Ozon R

Abstract

[alpha-32P]ATP was microinjected into Xenopus oocyte and neosynthesized cyclic AMP was isolated. Cholera toxin inhibited progesterone-induced maturation and stimulated after 3 h of preincubation the amount of neosynthesized cyclic AMP. Progesterone decreased the neosynthesis of cyclic AMP during the first hour following addition of the hormone.

MeSH Terms

1-Methyl-3-isobutylxanthine/pharmacology Animals Cholera Toxin/pharmacology Cyclic AMP/biosynthesis Female In Vitro Techniques Ovum/drug effects,metabolism Progesterone/pharmacology Xenopus

Chemicals

Progesterone Cholera Toxin Cyclic AMP 1-Methyl-3-isobutylxanthine

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Mulner O

Huchon D

Thibier C

Ozon R

Article Info

Journal

Biochimica et biophysica acta

Abbr.

Biochim Biophys Acta

ISSN

0006-3002

DOI

10.1016/0304-4165(79)90301-5

Published

1979-01-04

Pages

179-84

Language

English

Region

Netherlands

NLM ID

0217513

Subset

External Links

PubMed source DOI: 10.1016/0304-4165(79)90301-5

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Cyclic AMP synthesis in Xenopus laevis oocytes: inhibition by progesterone.

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