Gardimycin, a new antibiotic from Actinoplanes. III. Biological properties.

The Journal of antibiotics ·Vol. 29 ·No. 5 ·1976-05-00 ·Pages 511-5

Arioli V, Berti M, Silvestri LG

Abstract

The new antibiotic gardimycin has an interesting in vitro antibacterial activity against Gram-positive bacteria and Neisseria gonorrhoeae. Parenteral administration gives a high degree of protection against experimental infections in mice. It also shows some chemotherapeutic activity when given rectally.

MeSH Terms

Actinomycetales/metabolism Animals Anti-Bacterial Agents/analysis,pharmacology,therapeutic use Bacteria/drug effects Bacterial Infections/drug therapy Culture Media Drug Resistance, Microbial Drug Stability Female Hydrogen-Ion Concentration Male Mice Microbial Sensitivity Tests Peptides/analysis,pharmacology,therapeutic use Time Factors Yeasts/drug effects

Chemicals

Anti-Bacterial Agents Culture Media Peptides

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Arioli V

Berti M

Silvestri L G

Article Info

Journal

The Journal of antibiotics

Abbr.

J Antibiot (Tokyo)

ISSN

0021-8820

DOI

10.7164/antibiotics.29.511

Published

1976-05-00

Pages

511-5

Language

English

Region

Japan

NLM ID

0151115

Subset

External Links

PubMed source DOI: 10.7164/antibiotics.29.511 View journal details

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Gardimycin, a new antibiotic from Actinoplanes. III. Biological properties.

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