Home LiteratureArticle Details
PMID: 8417982 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Unequal exchange and meiotic instability of disease-resistance genes in the Rp1 region of maize.

Genetics ·Vol. 133 ·No. 1 ·1993-01-00 ·Pages 119-25

Sudupak MA, Bennetzen JL, Hulbert SH

Abstract

The Rp1 region of maize was originally characterized as a complex locus which conditions resistance to the fungus Puccinia sorghi, the causal organism in the common rust disease. Some alleles of Rp1 are meiotically unstable, but the mechanism of instability is not known. We have studied the role of recombination in meiotic instability in maize lines homozygous for either Rp1-J or Rp1-G. Test cross progenies derived from a line that was homozygous for Rp1-J, but heterozygous at flanking markers, were screened for susceptible individuals. Five susceptible individuals were derived from 9772 progeny. All five had nonparental combinations of flanking markers; three had one combination of recombinant flanking markers while the other two had the opposite pair. In an identical study with Rp1-G, 20 susceptible seedlings were detected out of 5874 test cross progeny. Nineteen of these were associated with flanking marker exchange, 11 and 8 of each recombinant marker combination. Our results indicate that unequal exchange is the primary mechanism of meiotic instability of Rp1-J and Rp1-G.

Related Genes
Rp1
MeSH Terms
Basidiomycota Blotting, Southern Crossing Over, Genetic DNA Genes, Plant Genetic Predisposition to Disease Heterozygote Homozygote Meiosis/genetics Plant Diseases/genetics,microbiology Recombination, Genetic Zea mays/genetics
Chemicals
DNA
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Sudupak M A
Department of Plant Pathology, Kansas State University, Manhattan 66506-5502.
Bennetzen J L
Hulbert S H
References (19)
19 references, click to expand
  1. Fine structure and instability of the Ml-a locus in barley.
    Genetics. 1985 Sep;111(1):113-30 PMID: 4029608
  2. Conversion and reciprocal exchange between tandem repeats in Drosophila melanogaster.
    Mol Gen Genet. 1989 Dec;220(1):140-6 PMID: 2514345
  3. Recombination at the human alpha-globin gene cluster: sequence features and topological constraints.
    Cell. 1987 May 8;49(3):369-78 PMID: 3032452
  4. Gene conversion, unequal crossing-over and mispairing at a non-tandem duplication during meiosis of Saccharomyces cerevisiae.
    Curr Genet. 1987;12(1):1-7 PMID: 3329573
  5. On the structure of a gene for disease resistance in maize.
    Proc Natl Acad Sci U S A. 1968 Dec;61(4):1300-5 PMID: 16591724
  6. Mechanisms of tandem duplication in the Duchenne muscular dystrophy gene include both homologous and nonhomologous intrachromosomal recombination.
    EMBO J. 1991 Sep;10(9):2471-7 PMID: 1868831
  7. Asymmetrical pairings of transposons in and proximal to the white locus of Drosophila account for four classes of regularly occurring exchange products.
    Proc Natl Acad Sci U S A. 1987 Jan;84(1):174-8 PMID: 3025852
  8. Unequal crossing-over between two alu-repetitive DNA sequences in the low-density-lipoprotein-receptor gene. A possible mechanism for the defect in a patient with familial hypercholesterolaemia.
    Eur J Biochem. 1987 Apr 1;164(1):77-81 PMID: 3549308
  9. Mapping RFLP loci in maize using B-A translocations.
    Genetics. 1989 Mar;121(3):583-90 PMID: 2565856
  10. Unequal crossing-over associated with asymmetrical synapsis between nomadic elements in the Drosophila melanogaster genome.
    Proc Natl Acad Sci U S A. 1983 Aug;80(16):5017-21 PMID: 16593354
  11. Genetics of disease resistance in plants.
    Annu Rev Genet. 1971;5:407-24 PMID: 16097661
  12. Recombination at the Rp1 locus of maize.
    Mol Gen Genet. 1991 May;226(3):377-82 PMID: 1674815
  13. The Waxy Locus in Maize. I. Intralocus Recombination Frequency Estimates by Pollen and by Conventional Analyses.
    Genetics. 1962 Jun;47(6):737-42 PMID: 17248109
  14. Meiotic recombination between duplicated genetic elements in Saccharomyces cerevisiae.
    Genetics. 1985 Feb;109(2):303-32 PMID: 3882522
  15. Gene mapping with recombinant inbreds in maize.
    Genetics. 1988 Mar;118(3):519-26 PMID: 3366363
  16. Genetic Fine Structure of the BRONZE Locus in Maize.
    Genetics. 1986 Aug;113(4):1021-36 PMID: 17246338
  17. Gene-for-gene complementarity in plant-pathogen interactions.
    Annu Rev Genet. 1990;24:447-63 PMID: 2088175
  18. Genes conferring specific plant disease resistance.
    Science. 1972 Jan 28;175(4020):375-80 PMID: 17731351
  19. GENETICS OF REACTION TO PUCCINIA SORGHI IN ELEVEN CORN INBRED LINES FROM CENTRAL AND SOUTH AMERICA.
    Phytopathology. 1965 Feb;55:193-7 PMID: 14272785
Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1093/genetics/133.1.119
Published
1993-01-00
Pages
119-25
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1205291
Subset
IM
External Links
PubMed source DOI: 10.1093/genetics/133.1.119 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2