An outbreak of infection caused by a gentamicin-resistant Staphylococcus aureus.

Journal of clinical pathology ·Vol. 30 ·No. 2 ·1977-02-00 ·Pages 165-7

Bint AJ, George RH, Healing DE, Wise R, Davies M

Abstract

An outbreak of infection caused by a strain of Staphylococcus aureus resistant to gentamicin and tobramycin and other antibiotics occurred in two wards in a hospital. Eight patients were colonized, of whom six had clinical infections. Previous administration of gentamicin appeared to predispose the patients to infection with the strain. Restriction of the use of gentamicin and tobramycin is essential to preserve their value in serious infections.

MeSH Terms

Anti-Bacterial Agents/pharmacology Cross Infection/etiology Disease Outbreaks Drug Resistance, Microbial Female Gentamicins/pharmacology Humans Male Staphylococcus aureus/drug effects Tobramycin/pharmacology

Chemicals

Anti-Bacterial Agents Gentamicins Tobramycin

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Bint A J

George R H

Healing D E

Wise R

Davies M

References (13)

13 references, click to expand

NEOMYCIN-RESISTANT STAPHYLOCOCCUS AUREUS IN A BURNS UNIT.
J Hyg (Lond). 1964 Jun;62:221-8 PMID: 14171272
Influence of neomycin sprays on the spread of resistant staphylococci.
Lancet. 1967 Nov 18;2(7525):1062-3 PMID: 4168538
Letter: Gentamicin-resistant escherichia coli.
Br Med J. 1974 Jun 15;2(5919):613 PMID: 4365671
Pseudomonas aeruginosa resistant to carbenicillin and gentamicin. Epidemiologic and clinical aspects in a cancer center.
Ann Intern Med. 1973 Nov;79(5):684-9 PMID: 4201634
Letter: Gentamicin-resistant Staphylococci.
Lancet. 1976 Mar 6;1(7958):543-4 PMID: 55819
Epidemic infection by a gentamicin-resistant Staphylococcus aureus in three hospitals.
Lancet. 1976 Feb 28;1(7957):464-6 PMID: 55729
Gentamicin resistance in Staphylococcus aureus.
Lancet. 1976 Jan 3;1(7949):20-1 PMID: 54520
Genetic basis, epidemiology, and future significance of antibiotic resistance in Staphylococcus aureus: a review.
J Clin Pathol. 1973 Dec;26(12):899-913 PMID: 4593862
Infection caused by Proteus mirabilis strains with transferrable gentamicin-resistance factors.
Lancet. 1975 Jun 21;1(7921):1355-7 PMID: 48945
Genetic control in methicillin-resistant strains of Staphylococcus aureus.
J Med Microbiol. 1972 Nov;5(4):497-508 PMID: 4486061
A gentamycin resistance plasmid in Staphylococcus aureus.
Ann Microbiol (Paris). 1975 Jul-Aug;126B(1):91-4 PMID: 129020
The acetyltransferase enzyme method for the assay of serum gentamicon concentrations and a comparison with other methods.
J Clin Pathol. 1975 Feb;28(2):140-5 PMID: 805161
Antibiotic resistance plasmids of Staphylococcus aureus and their clinical importance.
Bacteriol Rev. 1975 Mar;39(1):1-32 PMID: 1091256

Article Info

Journal

Journal of clinical pathology

Abbr.

J Clin Pathol

ISSN

0021-9746

DOI

10.1136/jcp.30.2.165

Published

1977-02-00

Pages

165-7

Language

English

Region

England

NLM ID

0376601

PMCID

PMC476343

Subset

External Links

PubMed source DOI: 10.1136/jcp.30.2.165 PMC Full Text View journal details

Analysis Services

An outbreak of infection caused by a gentamicin-resistant Staphylococcus aureus.

Contact

WeChat Official Account