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PMID: 8465606 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

The complete sequence of a 19,482 bp segment located on the right arm of chromosome II from Saccharomyces cerevisiae.

Yeast (Chichester, England) ·Vol. 9 ·No. 2 ·1993-02-00 ·Pages 189-99

Doignon F, Biteau N, Crouzet M, Aigle M

Abstract

We report here the sequence of a 19,482 bp DNA segment of chromosome II of Saccharomyces cerevisiae. The fragment contains 16 open reading frames (ORFs) covering 74% of the sequence. Four predicted products present homology with known proteins. The ORF YBR1732 exhibits a strong homology to serine hydroxymethyl transferase; the best score is 53.1% identity in 458 amino acids overlap with the serine hydroxymethyl transferase from rabbit liver. YBR1724, which shows homology with riboflavin synthase of Bacillus subtilis, is probably the RIB5 gene implied in riboflavine synthesis and mapped in this region. YBR1733 is homologous to rab protein and YBR1728 is presumably a GTPase activating protein.

Related Genes
MeSH Terms
Amino Acid Sequence Base Sequence Chimerin 1 Chromosomes, Fungal GTP-Binding Proteins/genetics Genes, Fungal/genetics Glycine Hydroxymethyltransferase/genetics Molecular Sequence Data Nerve Tissue Proteins/genetics Oncogene Proteins/genetics Open Reading Frames Protein-Tyrosine Kinases Proto-Oncogene Proteins Proto-Oncogene Proteins c-bcr Restriction Mapping Riboflavin Synthase/genetics Saccharomyces cerevisiae/genetics Sequence Analysis, DNA Sequence Homology, Amino Acid
Chemicals
Chimerin 1 Nerve Tissue Proteins Oncogene Proteins Proto-Oncogene Proteins Glycine Hydroxymethyltransferase Riboflavin Synthase Protein-Tyrosine Kinases Proto-Oncogene Proteins c-bcr GTP-Binding Proteins
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Doignon F
Laboratoire de Biologie Moléculaire et de Séquençage, Université de Bordeaux II, France.
Biteau N
Crouzet M
Aigle M
Article Info
Journal
Yeast (Chichester, England)
Abbr.
Yeast
ISSN
0749-503X
Published
1993-02-00
Pages
189-99
Language
English
Region
England
NLM ID
8607637
Subset
IM
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