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PMID: 8483901 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Predicting protein diffusion coefficients.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 90 ·No. 9 ·1993-05-01 ·Pages 3835-9

Brune D, Kim S

Abstract

Diffusion coefficients for proteins in water are predicted. The numerical method developed is general enough to be applied to a wide range of protein surface shapes, from rodlike to globular. Results are presented for lysozyme and tobacco mosaic virus, and they are compared with actual data and with predictions made by less general methods.

MeSH Terms

Diffusion Mathematics Models, Molecular Models, Theoretical Muramidase/chemistry Protein Conformation Proteins/chemistry Water

Chemicals

Proteins Water Muramidase

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Brune D

Department of Chemical Engineering, University of Wisconsin, Madison 53705.

Kim S

References (4)

4 references, click to expand

Hydration of proteins and polypeptides.
Adv Protein Chem. 1974;28:239-345 PMID: 4598824
Frictional models for stochastic simulations of proteins.
Biopolymers. 1988 Jun;27(6):1001-14 PMID: 3401553
On an exact starting expression for macromolecular hydrodynamic models.
Biopolymers. 1986 Apr;25(4):627-37 PMID: 3708107
Hydrodynamic properties of complex, rigid, biological macromolecules: theory and applications.
Q Rev Biophys. 1981 Feb;14(1):81-139 PMID: 7025081

Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.90.9.3835

Published

1993-05-01

Pages

3835-9

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC46400

Subset

External Links

PubMed source DOI: 10.1073/pnas.90.9.3835 PMC Full Text View journal details

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