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PMID: 8535142 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Induction of wound response genes in tomato leaves by bestatin, an inhibitor of aminopeptidases.

The Plant cell ·Vol. 7 ·No. 11 ·1995-11-00 ·Pages 1893-8

Schaller A, Bergey DR, Ryan CA

Abstract

Bestatin, an inhibitor of some aminopeptidases in plants and animals, is a powerful inducer of defense genes in tomato leaves; these genes are also induced by herbivore attacks, mechanical wounding, systemin, and methyl jasmonate. Unlike wounding and systemin, bestatin does not cause an increase in intracellular jasmonic acid concentrations, and inhibitors of the octadecanoid pathway do not inhibit induction by bestatin. Furthermore, defense genes were induced by bestatin in a mutant tomato line (JL-5) with a defect in the octadecanoid pathway. Bestatin therefore appears to be exerting its effects close to the level of transcriptional control of these genes, where it may be inhibiting a regulatory protease.

MeSH Terms
Aminopeptidases/antagonists & inhibitors Animals Base Sequence Gene Expression/drug effects Genes, Plant Leucine/analogs & derivatives,pharmacology Lycopersicon esculentum/drug effects,genetics,metabolism Molecular Sequence Data Mutation Oligonucleotide Probes Peptide Biosynthesis Peptides Plant Leaves Plant Proteins/biosynthesis Protease Inhibitors/metabolism,pharmacology Transcription, Genetic Wounds and Injuries
Chemicals
Oligonucleotide Probes Peptides Plant Proteins Protease Inhibitors systemin Aminopeptidases Leucine ubenimex
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Schaller A
Institute of Biological Chemistry, Washington State University, Pullman 99164-6340, USA.
Bergey D R
Ryan C A
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26 references, click to expand
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Article Info
Journal
The Plant cell
Abbr.
Plant Cell
ISSN
1040-4651
DOI
10.1105/tpc.7.11.1893
Published
1995-11-00
Pages
1893-8
Language
English
Region
England
NLM ID
9208688
PMCID
PMC161047
Subset
IM
External Links
PubMed source DOI: 10.1105/tpc.7.11.1893 PMC Full Text View journal details
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