[Calculation of the Chance of paternity exclusion and of the probability of paternity for the HLA system (author's transl)].
Berechnung der Vaterschaftsausschlusschance und der Vaterschaftswahrscheinlichkeit im HLA System
The genetics of the serological defined SD antigens of the HLA system, which are governed by three closely linked loci (HLA-A, HLA-B and HLA-C) situated on the chromosome C6, are described. Regarding patermity testing, only the antigens coded by the loci HLA-A and HLA-B are used routinely up to now. Because of the strong linkage disequilibrium between these two loci, they cannot be considered as independent. The influence of the linkage disequilibrium on the calculation of the chance of paternity exclusion and of the plausibility of paternity is discussed and demonstrated in several examples.
4 references, click to expand
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[Frequencies of hl-a phenotypes, genes, and haplotypes in the viennese population (author's transl)].Wien Klin Wochenschr. 1975 Aug 15;87(15):488-92 PMID: 1226756
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[Calculation of the chance of paternity exclusion for the HL-A system (author's transl)].Z Immunitatsforsch Exp Klin Immunol. 1975 Nov;150(5):447-57 PMID: 133546
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[Calculation of the plausibility of paternity in the HL-A system (author's transl)].Z Immunitatsforsch Exp Klin Immunol. 1972 Jul;144(1):18-27 PMID: 4283238
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[The HL-A-system in paternity testing (author's transl)].Z Rechtsmed. 1974;75(2):81-103 PMID: 4614631
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