New tumor antigens recognized by T cells.

Current opinion in immunology ·Vol. 7 ·No. 5 ·1995-10-00 ·Pages 674-81

Van den Eynde B, Brichard VG

Abstract

A series of tumor cell antigens that are recognized by cytolytic T lymphocytes has been characterized this year. Besides the antigens derived from proteins specifically expressed in tumors, many melanoma antigens derive from melanocytic differentiation proteins. In addition, antigens unique to individual tumors result from mutations in ubiquitously expressed genes.

MeSH Terms

Amino Acid Sequence Animals Antigens, Differentiation/immunology Antigens, Neoplasm/immunology,isolation & purification Biomarkers, Tumor/immunology Humans Melanoma/immunology Melanoma, Experimental/immunology Mice Molecular Sequence Data T-Lymphocytes/immunology

Chemicals

Antigens, Differentiation Antigens, Neoplasm Biomarkers, Tumor

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Van den Eynde B

Ludwig Institute for Cancer Research, Brussels, Belgium.

Brichard V G

Article Info

Journal

Current opinion in immunology

Abbr.

Curr Opin Immunol

ISSN

0952-7915

DOI

10.1016/0952-7915(95)80076-x

Published

1995-10-00

Pages

674-81

Language

English

Region

England

NLM ID

8900118

Subset

External Links

PubMed source DOI: 10.1016/0952-7915(95)80076-x View journal details

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