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PMID: 8594576 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Progress with the PRINTS protein fingerprint database.

Nucleic acids research ·Vol. 24 ·No. 1 ·1996-01-01 ·Pages 182-8

Attwood TK, Beck ME, Bleasby AJ, Degtyarenko K, Parry Smith DJ

Abstract

PRINTS is a compendium of protein motif 'fingerprints' derived from the OWL composite sequence database. Fingerprints are groups of motifs within sequence alignments whose conserved nature allows them to be used as signatures of family membership. To date, 400 fingerprints have been constructed and stored in Prints, the size of which has doubled in the last year. The current version, 9.0, encodes approximately 2000 motifs, covering a range of globular and membrane proteins, modular polypeptides, and so on. Fingerprints inherently offer improved diagnostic reliability over single motif methods by virtue of the mutual context provided by motif neighbours. PRINTS thus provides a useful adjunct to the widely used PROSITE dictionary of patterns. The database is now accessible via the Database Browser on the UCL Bioinformatics server at http://www.biochem.ucl.ac.uk/bsm/dbbrowser .

MeSH Terms
Amino Acid Sequence Computer Communication Networks Databases, Factual Proteins/chemistry,genetics Sequence Alignment
Chemicals
Proteins
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Attwood T K
Department of Biochemistry, University College London, UK.
Beck M E
Bleasby A J
Degtyarenko K
Parry Smith D J
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/24.1.182
Published
1996-01-01
Pages
182-8
Language
English
Region
England
NLM ID
0411011
PMCID
PMC145564
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/24.1.182 PMC Full Text View journal details
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