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PMID: 8614608 Published · ppublish English Journal Article Review

Necrotizing enterocolitis: the search for a unifying pathogenic theory leading to prevention.

Pediatric clinics of North America ·Vol. 43 ·No. 2 ·1996-04-00 ·Pages 409-32

Neu J

Abstract

During the past two decades, necrotizing enterocolitis has emerged as a major cause of mortality and morbidity in premature infants. The specific cause of the disease remains enigmatic, but several putative risk factors provide clues to a pathophysiology that seems to be multifactorial. With the use of newly developed scientific tools, an understanding of the basic pathophysiologic cascade that causes necrotizing enterocolitis is emerging, providing hope for improved treatment and prevention.

MeSH Terms
Anti-Bacterial Agents/therapeutic use Enteral Nutrition Enterocolitis, Pseudomembranous/diagnosis,microbiology,physiopathology,prevention & control Humans Infant, Newborn Infant, Premature, Diseases/diagnosis,microbiology,physiopathology,prevention & control Primary Prevention/methods Risk Factors Severity of Illness Index
Chemicals
Anti-Bacterial Agents
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Neu J
Department of Pediatrics, University of Florida College of Medicine, Gainesville, USA.
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Article Info
Journal
Pediatric clinics of North America
Abbr.
Pediatr Clin North Am
ISSN
0031-3955
DOI
10.1016/s0031-3955(05)70413-2
Published
1996-04-00
Pages
409-32
Language
English
Region
United States
NLM ID
0401126
PMCID
PMC7127724
Subset
IM
External Links
PubMed source DOI: 10.1016/s0031-3955(05)70413-2 PMC Full Text View journal details
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