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PMID: 8635921 Published · ppublish English Journal Article Review

An introduction to oxygen free radicals.

Heart & lung : the journal of critical care ·Vol. 25 ·No. 3 ·1996-00-00 ·Pages 200-9; quiz 210-1

Kerr ME, Bender CM, Monti EJ

Abstract

Oxygen free radicals are byproducts from the fundamental metabolic activities within the body. Normally, radicals are neutralized by enzymatic activity or natural antioxidants. Thus the generation of free radicals poses no problem so long as the balance between oxygen radical production and eradication remains in balance. There are multiple medical conditions, such as myocardial infarction, carcinogenesis, and neurologic trauma, to name a few, that may be aggravated by the presence of oxygen free radicals. This article will present an overview of oxygen free radicals: their normal formation and control and how they might further injure tissue in particular diseases. The implications for health care professionals are highlighted.

MeSH Terms
Antioxidants/metabolism,therapeutic use Arteriosclerosis/etiology,prevention & control Brain Injuries/etiology Free Radicals/adverse effects Humans Neoplasms/etiology Oxygen/adverse effects,metabolism Reactive Oxygen Species/adverse effects Reperfusion Injury/etiology
Chemicals
Antioxidants Free Radicals Reactive Oxygen Species Oxygen
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Kerr M E
University of Pittsburgh School of Nursing, Pennsylvania 15261-1000, USA.
Bender C M
Monti E J
Article Info
Journal
Heart & lung : the journal of critical care
Abbr.
Heart Lung
ISSN
0147-9563
Published
1996-00-00
Pages
200-9; quiz 210-1
Language
English
Region
United States
NLM ID
0330057
Subset
IM
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