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PMID: 86373 Published · ppublish English Case Reports Journal Article

Health problems of anaesthetists and their families in the West Midlands.

British medical journal ·Vol. 1 ·No. 6166 ·1979-03-24 ·Pages 779-84

Tomlin PJ

Abstract

A survey of all anaesthetists in the West Midlands region--that is, 10% of all the anaesthetists in England and Wales--showed that one in 10 of their children had been referred to a consultant because of a congenital or nonacquired anomaly. Abortions among anaesthetists' families were also common but more so when the mother was an anaesthetist. The anomalies were concentrated particularly in the central nervous system and musculoskeletal system, and girls were worst affected. The mean birth weights were below normal, more so when the mothers were anaesthetists. Girls with anomalies were particularly underweight. Other effects observed were unexpected infertility, cancer both in the adults and in the children, and, possibly, impaired intellectual development in the children. Many anaesthetising areas were inadequately ventilated, and scavenging devices despite their inefficiency are recommended as a stopgap measure. The results of the study closely resemble those of other studies with similar high response rates to requests for information.

MeSH Terms
Abnormalities, Drug-Induced/etiology Abortion, Spontaneous/chemically induced Air Pollutants/adverse effects Air Pollutants, Occupational/adverse effects Anesthesiology Anesthetics/adverse effects Child Developmental Disabilities/chemically induced England Female Health Surveys Humans Infant Infant, Newborn Infant, Small for Gestational Age Infertility/chemically induced Male Neoplasms/chemically induced,genetics Occupational Diseases/chemically induced,genetics Operating Rooms/standards Pregnancy Sex Factors Ventilation
Chemicals
Air Pollutants Air Pollutants, Occupational Anesthetics
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Tomlin P J
References (21)
21 references, click to expand
  1. Cancer and congenital anomalies associated with anesthetics.
    Ann N Y Acad Sci. 1976;271:58-66 PMID: 1069540
  2. Testicular reaction to prolonged exposure to nitrous oxide.
    Anesthesiology. 1976 Feb;44(2):104-13 PMID: 1082731
  3. Critique: occupational disease among operating room personnel.
    Anesthesiology. 1975 May;42(5):608-11 PMID: 1130725
  4. Trace concentrations of anesthetic gases: a critical review of their disease potential.
    Anesth Analg. 1978 May-Jun;57(3):328-45 PMID: 350092
  5. Epidemiological studies of the occupational hazards of anaesthesia--a review.
    Anaesthesia. 1978 May;33(5):430-8 PMID: 352182
  6. Balanced regional analgesia--an hypothesis.
    Can Anaesth Soc J. 1978 Sep;25(5):412-5 PMID: 359111
  7. Anaesthetic practice and pregnancy. Controlled survey of women anaesthetists in the United Kingdom.
    Lancet. 1972 Jun 17;1(7764):1326-8 PMID: 4113412
  8. Birth defects among children of nurse-anesthetists.
    Anesthesiology. 1974 Oct;41(4):341-4 PMID: 4412215
  9. Miscarriages among operating theatre staff.
    Acta Anaesthesiol Scand Suppl. 1973;53:37-42 PMID: 4530586
  10. Effects of halothane on DNA synthesis and mitosis in root tip meristems of Vicia faba.
    Br J Anaesth. 1974 Sep;46(9):653-7 PMID: 4621173
  11. Incidence of cancer among Michigan nurse-anesthetists.
    Anesthesiology. 1973 Mar;38(3):260-3 PMID: 4698146
  12. A prospective survey of anesthesiologist mortality, 1967-1971.
    Anesthesiology. 1974 Jul;41(1):71-4 PMID: 4857954
  13. The teratogenicity of halothane in the rat.
    Anesthesiology. 1968 Nov-Dec;29(6):1167-73 PMID: 4973213
  14. [Teratogenic effects of inhalation anesthetics].
    Nord Med. 1970 Apr 16;83(16):498-500 PMID: 5426415
  15. Incidence of congenital abnormalities in Liverpool, 1960-64.
    Br J Prev Soc Med. 1968 Jan;22(1):36-7 PMID: 5636974
  16. Causes of death among anesthesiologists: a 20-year survey.
    Anesthesiology. 1968 May-Jun;29(3):565-9 PMID: 5647504
  17. The incidence of malformations in Birmingham, England, 1950-1959.
    Teratology. 1968 Aug;1(3):263-80 PMID: 5759547
  18. Teratogenic activity of nitrous oxide.
    Nature. 1967 Apr 8;214(5084):146-8 PMID: 6034210
  19. Outcome of pregnancy among women in anaesthetic practice.
    Lancet. 1977 Jan 1;1(8001):34-6 PMID: 63667
  20. Chronic exposure of rats to inhalational anaesthetic agents [proceedings].
    J Physiol. 1978 Mar;276:24P-25P PMID: 650445
  21. Megaloblastic haemopoiesis in patients receiving nitrous oxide.
    Lancet. 1978 Aug 12;2(8085):339-42 PMID: 79709
Article Info
Journal
British medical journal
Abbr.
Br Med J
ISSN
0007-1447
Published
1979-03-24
Pages
779-84
Language
English
Region
England
NLM ID
0372673
PMCID
PMC1598404
Subset
IM
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