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PMID: 8640533 Published · ppublish English Journal Article Review

Current status of structure-activity relationships of platinum anticancer drugs: activation of the trans geometry.

Metal ions in biological systems ·Vol. 32 ·1996-00-00 ·Pages 603-39

Farrell N

Abstract

暂无摘要

MeSH Terms
Animals Antineoplastic Agents/chemistry,therapeutic use,toxicity Binding Sites Cell Survival/drug effects Cisplatin/chemistry,therapeutic use,toxicity DNA/chemistry,metabolism DNA Damage DNA Replication/drug effects Female Humans Leukemia L1210 Mice Models, Structural Nucleic Acid Conformation Ovarian Neoplasms/drug therapy Stereoisomerism Structure-Activity Relationship
Chemicals
Antineoplastic Agents transplatin DNA Cisplatin
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Farrell N
Department of Chemistry, Virginia Commonwealth University, Richmond 23284-2006, USA.
Article Info
Journal
Metal ions in biological systems
Abbr.
Met Ions Biol Syst
ISSN
0161-5149
Published
1996-00-00
Pages
603-39
Language
English
Region
United States
NLM ID
0406332
Subset
IM
External Links
PubMed source View journal details
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