[Effect of the spread of the process and treatment on the phenotype of peripheral blood lymphocytes in patients with prostatic cancer].

A wide panel of monoclonal antibodies to differentiation antigens has been originally used to determine phenotype of peripheral blood lymphocytes in patients with prostatic cancer (PC). Patients with local PC exhibited marked lymphocytopenia existent in vertually all populations and subpopulations. In generalized PC the above changes are more pronounced. Treatment of PC adds to immunodepression observed in this disease. Thus, immunotherapy as an adjuvant modality of PC treatment is quite appropriate.