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PMID: 869952 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Increased frequency of HLA-Cw3 and HLA-Dw4 in rheumatoid arthritis.

Arthritis and rheumatism ·Vol. 20 ·No. 5 ·1977-06-00 ·Pages 1037-42

McMichael AJ, Sasazuki T, McDevitt HO, Payne RO

Abstract

Thirty-nine patients with rheumatoid arthritis were HLA typed for the full range of A and B locus specificities and for Cw3 and Dw4. HLA-Dw4 was significantly more frequent in patients (36%) than in controls (13%). The frequency of Cw3 was also increased, probably because this allele is in linkage disequilibrium with Dw4.

MeSH Terms
Alleles Arthritis, Rheumatoid/genetics,immunology Female Gene Frequency Genetic Linkage HLA Antigens/analysis Histocompatibility Antigens/analysis Homozygote Humans Male
Chemicals
HLA Antigens Histocompatibility Antigens
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
McMichael A J
Sasazuki T
McDevitt H O
Payne R O
Article Info
Journal
Arthritis and rheumatism
Abbr.
Arthritis Rheum
ISSN
0004-3591
DOI
10.1002/art.1780200501
Published
1977-06-00
Pages
1037-42
Language
English
Region
United States
NLM ID
0370605
Subset
IM
External Links
PubMed source DOI: 10.1002/art.1780200501 View journal details
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