Synthesis and pharmacological evaluation of N-aryl(pyrimidinyl) piperazinylalkyl (hydroxyalkyl) derivatives of 1,2,3,4-tetra- and 1,2,3,4,5,6-hexahydropyrido[3,4-d]pyridazines.

Farmaco (Societa chimica italiana : 1989) ·Vol. 51 ·No. 6 ·1996-10-21

Sladowska H, Potoczek J, Rajtar G, Sieklucka-Dziuba M, Młynarczyk M, Kleinrok Z

Abstract

The synthesis of N-aryl(pyrimidinyl)piperazinylalkyl(hydroxyalkyl) derivatives of 1,4-dioxo(1,4,5-trioxo)-1,2,3,4-tetra (and 1,2,3,4,5,6-hexa)hydropyrido[3,4-d]pyridazines is described. Some of them show biological activity in the preliminary pharmacological tests.

Article Info

Journal

Farmaco (Societa chimica italiana : 1989)

Abbr.

Farmaco

ISSN

0014-827X

Published

1996-10-21

Indexed

1996-10-21

Updated

2008-11-21

Language

English

Country/Region

France

NLM ID

8912641

External Links

PubMed source

Analysis Services

Synthesis and pharmacological evaluation of N-aryl(pyrimidinyl) piperazinylalkyl (hydroxyalkyl) derivatives of 1,2,3,4-tetra- and 1,2,3,4,5,6-hexahydropyrido[3,4-d]pyridazines.

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