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PMID: 877552 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Induction of acetylcholinesterase activity by beta-ecdysone in a Drosophila cell line.

Science (New York, N.Y.) ·Vol. 197 ·No. 4300 ·1977-07-15 ·Pages 275-7

Cherbas P, Cherbas L, Williams CM

Abstract

When cells of the Drosophila Kc-H line are treated with larger than or equal to 10(-8) molar beta-ecdysone, they extend long processes and acquire acetylcholinesterase activity. Thus, this permanent line, derived originally from embryol cultures, may be composed of cells having some neural or glial characteristics.

MeSH Terms
Acetylcholine/metabolism Acetylcholinesterase/biosynthesis Cell Differentiation/drug effects Cell Line Cholinesterase Inhibitors Drosophila/enzymology Ecdysterone/pharmacology Enzyme Induction/drug effects Kinetics Neurons/enzymology Physostigmine/pharmacology
Chemicals
Cholinesterase Inhibitors Ecdysterone Physostigmine Acetylcholinesterase Acetylcholine
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Cherbas P
Cherbas L
Williams C M
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.877552
Published
1977-07-15
Pages
275-7
Language
English
Region
United States
NLM ID
0404511
Subset
IM
External Links
PubMed source DOI: 10.1126/science.877552 View journal details
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