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PMID: 8794089 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Channels in transporters.

Current opinion in neurobiology ·Vol. 6 ·No. 3 ·1996-06-00 ·Pages 294-302

Sonders MS, Amara SG

Abstract

Recent electrophysiological investigations of plasma membrane neurotransmitter transporters have shown that carriers can function in ways similar to ion channels. The results of these studies reveal underlying mechanisms not encompassed by classic carrier models and support an emerging view that transporter-mediated ionic currents may contribute to signaling in the nervous system.

MeSH Terms

Amino Acid Transport Systems Animals Biogenic Amines/metabolism Biological Transport Carrier Proteins/chemistry,metabolism,physiology Electric Conductivity Electrophysiology Humans Ion Channels/physiology Ions Mathematics

Chemicals

Amino Acid Transport Systems Biogenic Amines Carrier Proteins Ion Channels Ions

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Sonders M S

Howard Hughes Medical Institute and Vollum Institute, Oregon Health Sciences University, Portland, Oregon 97201, USA.

Amara S G

Article Info

Journal

Current opinion in neurobiology

Abbr.

Curr Opin Neurobiol

ISSN

0959-4388

DOI

10.1016/s0959-4388(96)80111-5

Published

1996-06-00

Pages

294-302

Language

English

Region

England

NLM ID

9111376

Subset

Grants

NIDA NIH HHS · DA07595 · United States

NINDS NIH HHS · NS33273 · United States

External Links

PubMed source DOI: 10.1016/s0959-4388(96)80111-5 View journal details

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Channels in transporters.

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